UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 4
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
( ) Check this box if no longer subject to Section 16.
Form 4 or Form 5 obligations may continue. See Instructions 1(b).
1. Name and Address of Reporting Person
   Knopf, Gail H.
   500  West Main Street
   Louisville,, KY  40202
   USA
2. Issuer Name and Ticker or Trading Symbol
   Humana Inc.
   HUM
3. IRS or Social Security Number of Reporting Person (Voluntary)
   
4. Statement for Month/Year
   March 1997
5. If Amendment, Date of Original (Month/Year)
   
6. Relationship of Reporting Person(s) to Issuer (Check all applicable)
   ( ) Director ( ) 10% Owner (X) Officer (give title below) ( ) Other
   (specify below)
   Vice President-Information Systems
7. Individual or Joint/Group Filing (Check Applicable Line)
   (X) Form filed by One Reporting Person
   ( ) Form filed by More than One Reporting Person
___________________________________________________________________________________________________________________________________ Table I -- Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned | ___________________________________________________________________________________________________________________________________| 1. Title of Security |2. |3. |4.Securities Acquired (A) |5.Amount of |6.Dir |7.Nature of Indirect | | Transaction | or Disposed of (D) | Securities |ect | Beneficial Ownership | | | | | Beneficially |(D)or | | | | | | | A/| | Owned at |Indir | | | Date |Code|V| Amount | D | Price | End of Month |ect(I)| | ___________________________________________________________________________________________________________________________________| Common (1) |3/31/9|M | |10,000 |A |6.5625 | | | | |7 | | | | | | | | | - -----------------------------------------------------------------------------------------------------------------------------------| Common(1) |3/31/9|S | |10,000 |D |21.5 |1,000 |D | | |7 | | | | | | | | | - -----------------------------------------------------------------------------------------------------------------------------------| Common(1) | | | | | | |7,947.8 |I |HRSP(2) | - -----------------------------------------------------------------------------------------------------------------------------------| ___________________________________________________________________________________________________________________________________| ___________________________________________________________________________________________________________________________________ Table II -- Derivative Securitites Acquired, Disposed of, or Beneficially Owned | ___________________________________________________________________________________________________________________________________| 1.Title of Derivative |2.Con- |3. |4. |5.Number of De |6.Date Exer|7.Title and Amount |8.Price|9.Number |10.|11.Nature of| Security |version |Transaction | rivative Secu |cisable and| of Underlying |of Deri|of Deriva |Dir|Indirect | |or Exer | | | rities Acqui |Expiration | Securities |vative |tive |ect|Beneficial | |cise | | | red(A) or Dis |Date(Month/| |Secu |Securities |(D)|Ownership | |Price of| | | posed of(D) |Day/Year) | |rity |Benefi |or | | |Deriva- | | | |Date |Expir| | |ficially |Ind| | |tive | | | | A/|Exer-|ation| Title and Number | |Owned at |ire| | |Secu- | | | | | D |cisa-|Date | of Shares | |End of |ct | | |rity |Date |Code|V| Amount | |ble | | | |Month |(I)| | ___________________________________________________________________________________________________________________________________| Option (3) |8.6498 | | | | | |7/6/9|7/6/9|Common (1) |10,000 |D | | | | | | | | | | |1-2 |9 | | | | | | | - -----------------------------------------------------------------------------------------------------------------------------------| Option(4) |11.0131 | | | | | |9/13/|9/13/|Common (1) |4,500 |D | | | | | | | | | | |91-3 |00 | | | | | | | - -----------------------------------------------------------------------------------------------------------------------------------| Option(4) |8.9098 | | | | | |11/18|11/18|Common (1) |4,500 |D | | | | | | | | | | |/92-4|/01 | | | | | | | - -----------------------------------------------------------------------------------------------------------------------------------| Option(4) |6.5625 |3/31/|M | |10,000 |D |4/14/|4/14/|Common (1) |100,000|D | | | | | |97 | | | | |95-8 |03 | | | | | | | - -----------------------------------------------------------------------------------------------------------------------------------| Option(4) |23.0625 | | | | | |1/12/|1/12/|Common (1) |50,000 |D | | | | | | | | | | |96-8 |05 | | | | | | | - -----------------------------------------------------------------------------------------------------------------------------------| | | | | | | | | | | | | | | | ___________________________________________________________________________________________________________________________________|
Explanation of Responses: (1) Each share of Common Stock contains a Right adopted on March 5, 1987, as amended and restated on February 14, 1996, pursuant to the Company Rights Agreement, which entitles holders of the Company's Common Stock, in the event certain specified events occur, to acquire 1/100th of a share of Series A Participating Preferred Stock at a price of $145 per frctional share. (2) Shares held for my benefit as of January 31, 1997 under the Humana Retirement & Savings Plan ("HRSP") exempt under Rule 16b-3(c). (3) Right to buy pursuant to the Company's 1981 Non-Qualified Stock Option Plan. (4) Right to buy pursuant to the Company's 1989 Stock Option Plan for Employees.